An enzyme immunoassay for the quantitative measurement of testosterone in serum and plasma. Testosterone (17Beta-hydroxy-4-androstene-3-one) is a C19 steroid with an unsaturated bond between C-4 and C-5, a ketone group in C-3 and a hydroxyl group in the Beta position at C-17. This steroid hormone has a molecular weight of 288.47. Testosterone is the most important androgen secreted into the blood. In males, testosterone is secreted primarily by the Leydig cells of the testes; in females ca. 50% of circulating testosterone is derived from peripheral conversion of androstenedione, ca. 25% from the ovary and ca. 25% from the adrenal glands. Testosterone is responsible for the development of secondary male sex characteristics and its measurements are helpful in evaluating the hypogonadal states.
Enzyme immunoassay for the in vitro diagnostic quantitative measurement of active free progesterone (a female hormone) in saliva. Measurements obtained by this device may be used in the diagnosis and treatment of disorders of the ovaries or placenta and can be used as an aid for prediction of ovulation. Progesterone (4-pregnene-3, 20-dione) is a C21 steroid hormone containing a keto-group (at C-3) and a double bond between C-4 and C-5.
The DRG Salivary Hepcidin ELISA is an enzyme immunoassay for the quantitative measurement of hepcidin in saliva. Hepcidin is an iron homeostasis regulator peptide. The bioactive peptide hepcidin-25 is generated predoiminantly in the liver by proteolytic cleavage of the C-terminal 25 amino acids of prohepcidin (1).
An enzyme immunoassay for the quantitative in vitro diagnostic measurement of active free 17 hydroxyprogesterone in saliva. Measurements of 17-hydroxyprogesterone are used as an aid in the diagnosis of various disorders of the adrenal glands or the ovaries, and as an aid in the diagnosis of late onset of 21-hydroxylase deficiency, a common cause of Congenital Adrenal Hyperplasia. This test is not intended for newborn screening. The steroid 17-Alpha-Hydroxyprogesterone (17-Alpha-OHP) is produced by both the adrenal cortex and gonads. Even though 17-Alpha-OHP has relatively little progestational activity, it is of intense clinical interest because it is the immediate precursor to 11-desoxycortisol (Cpd-S).
An enzyme immunoassay for the quantitative determination of progesterone in serum and plasma. Progesterone (pregn-4-ene-3, 20-dione) is a C21 steroid hormone containing a keto-group (at C-3) and a double bond between C-4 and C-5 (?4). This steroid hormone is a female sex hormone which, in conjunction with estrogens, regulates the accessory organs during the menstrual cycle and it is particularly important in preparing the endometrium for the implantation of the blastocyte and in maintaining pregnancy. In non-pregnant women progesterone is mainly secreted by the corpus luteum whereas in pregnancy the placenta becomes the major source.
A high sensitive enzyme immunoassay for the quantitative measurement of Hepcidin-25 in serum or plasma (EDTA-, heparin- or citrate plasma). This product is for Research Use Only; International customers contact your representative to receive information about the CE marked version. The DRG Hepcidin 25 (bioactive) HS ELISA Kit is a solid phase enzyme-linked immunosorbent assay (ELISA) based on the principle of competitive binding. The microtiter wells are coated with a monoclonal (mouse) antibody directed towards an antigenic site of the Hepcidin-25 molecule.
An enzyme immunoassay for the quantitative measurement of DHEA-S in serum and plasma. Dehydroepiandrosterone (5-Androstene-3Beta-0L-17-one, Androstenolone, Dehydroisoandrosterone, Transdehydroandrosterone, DHEA) is a steroid hormone present in blood mostly in its sulfate form (DHEA S). DHEA-S is a more specific product of the adrenals and measurements of this steroid are widely used in clinical practice. The clinical importance of plasma assays of DHEA-S is associated with the diagnosis of adrenal hyperplasia and differential diagnosis of hirsutism (1).
An enzyme immunoassay for the quantitative measurement of dehydroepiandrosterone (DHEA) in serum and plasma. Dehydroepiandrosterone (DHEA; androstenolone; 3b-hydroxy-5-androsten-17-one) is a C19 steroid produced in the adrenal cortex and, to a lesser extent, gonads. DHEA serves as a precursor in testosterone and estrogen synthesis. DHEA has a rapid metabolic clearance rate as compared to its sulfated conjugate, DHEA-S. Because of this, serum DHEA levels are 100-1000 fold lower than DHEA-S levels. Serum DHEA levels are relatively high in the fetus and neonate, low during childhood, and increase again during puberty.
A high sensitivity enzyme immunoassay for the quantitative determination of C-reactive protein (CRP) concentration in serum. C- Reactive protein (CRP) was identified by Tilet and Francis (1930) in the plasma of patients with pneumonia, and was named for its ability to bind and precipitate the C-polysaccharide of pneumococcus.1,2 It is an alpha globulin with a molecular mass of approximately 110,000 to 140,000 daltons, and is composed of five identical subunits, which are noncovalently assembled as a cyclic pentamer.3 CRP is synthesized in the liver and is normally present as a trace constituent of serum or plasma at levels less than 0.3 mg/dl.2,4,5,6 Its physiological roles are numerous and varied, but with several functions similar to those of immunoglobulins, CRP appears to function in host defense.
An enzyme immunoassay for the quantitative measurement of 17-Alpha-OH progesterone (17-Alpha-OHP) in serum or plasma (EDTA-, heparin- or citrate plasma). The steroid 17-Alpha-Hydroxyprogesterone (17-Alpha-OHP) is produced by both the adrenal cortex and gonads. Even though 17-Alpha-OHP has relatively little progestational activity, it is of intense clinical interest because it is the immediate precursor to 11-desoxycortisol (Cpd-S). Because Cpd-S is produced by 21-hydroxylation of 17-Alpha-OHP, measurement of 17-Alpha-OHP is a useful indirect indicator of 21-hydroxylase activity.